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Saturday, April 2, 2011

Interactive MDS analysis of North European Americans


Here I ran my white American project members against sample sets from the UK, Ireland, Scandinavia, France, Poland, Germany, South and West Finland, and others. I chose these reference samples to help flesh out potential signals of ancestry from different parts of North, Central and Eastern Europe. On the other hand, I left out other references from the north, like the Lithuanians, who tend to polarize Northern Europe into east and west, and contract the western cluster. I don't know what they do this, because from what I've just seen, they're really not very different from Northwest Europeans at haploblock level (results of that analysis to be published here soon). Perhaps it's a result of some freaky allele frequencies due to founder effect? Anyway, refer to the "Test samples" sheet to see which MDS you're on, and follow the instructions below...

- download Gnuplot

- unpack Gnuplot

- download the MDS data NEU_MDS.zip

- place the relevant mds.dat into the "binary" Gnuplot folder

- type: splot 'mds1.dat' using 3:4:5:1 with labels

- spin the plot around and find some informative angles

To get large png files of the angles you like, say 2000x1500 pixels, try...

- type: set term png size 2000, 1500

- type: set output "mds1.png"

- type: splot 'mds1.dat' using 3:4:5:1 with labels




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